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Filters: Keyword is Extracellular Matrix  [Clear All Filters]
Journal Article
DuFort CC, Paszek MJ, Weaver VM.  2011.  Balancing forces: architectural control of mechanotransduction.. Nat Rev Mol Cell Biol. 12(5):308-19.
Weaver VM, Lelièvre S, Lakins JN, Chrenek MA, Jones JCR, Giancotti F, Werb Z, Bissell MJ.  2002.  beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium.. Cancer Cell. 2(3):205-16.
Zahir N, Weaver VM.  2004.  Death in the third dimension: apoptosis regulation and tissue architecture.. Curr Opin Genet Dev. 14(1):71-80.
Miroshnikova YA, Jorgens DM, Spirio L, Auer M, Sarang-Sieminski AL, Weaver VM.  2011.  Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties.. Phys Biol. 8(2):026013.
Lakins JN, Chin AR, Weaver VM.  2012.  Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels.. Methods Mol Biol. 916:317-50.
Lu P, Weaver VM, Werb Z.  2012.  The extracellular matrix: a dynamic niche in cancer progression.. J Cell Biol. 196(4):395-406.
Frantz C, Stewart KM, Weaver VM.  2010.  The extracellular matrix at a glance.. J Cell Sci. 123(Pt 24):4195-200.
Lu P, Takai K, Weaver VM, Werb Z.  2011.  Extracellular matrix degradation and remodeling in development and disease.. Cold Spring Harb Perspect Biol. 3(12)
Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ.  2009.  Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension.. Mol Biol Cell. 20(14):3224-38.
Yu H, Mouw JKay, Weaver VM.  2011.  Forcing form and function: biomechanical regulation of tumor evolution.. Trends Cell Biol. 21(1):47-56.
Weaver VM, Fischer AH, Peterson OW, Bissell MJ.  1996.  The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay.. Biochem Cell Biol. 74(6):833-51.
Lopez JI, Kang I, You W-K, McDonald DM, Weaver VM.  2011.  In situ force mapping of mammary gland transformation.. Integr Biol (Camb). 3(9):910-21.
Paszek MJ, Boettiger D, Weaver VM, Hammer DA.  2009.  Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate.. PLoS Comput Biol. 5(12):e1000604.
Kass L, Erler JT, Dembo M, Weaver VM.  2007.  Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis.. Int J Biochem Cell Biol. 39(11):1987-94.
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SFT, Csiszar K, Giaccia A, Weninger W et al..  2009.  Matrix crosslinking forces tumor progression by enhancing integrin signaling.. Cell. 139(5):891-906.
Kumar S, Weaver VM.  2009.  Mechanics, malignancy, and metastasis: the force journey of a tumor cell.. Cancer Metastasis Rev. 28(1-2):113-27.
Cassereau L, DuFort CC, Weaver VM.  2012.  Morphogenesis: Laying down the tracks.. Nat Mater. 11(6):490-2.
Tang Y, R Rowe G, Botvinick EL, Kurup A, Putnam AJ, Seiki M, Weaver VM, Keller ET, Goldstein S, Dai J et al..  2013.  MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.. Dev Cell. 25(4):402-16.
Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM.  2009.  Multiscale modeling of form and function.. Science. 324(5924):208-12.
Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ.  1997.  Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies.. J Cell Biol. 137(1):231-45.
Schmeichel KL, Weaver VM, Bissell MJ.  1998.  Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype.. J Mammary Gland Biol Neoplasia. 3(2):201-13.
Lelièvre SA, Weaver VM, Nickerson JA, Larabell CA, Bhaumik A, Petersen OW, Bissell MJ.  1998.  Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus.. Proc Natl Acad Sci U S A. 95(25):14711-6.