The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L et al.. 2014. The cancer glycocalyx mechanically primes integrin-mediated growth and survival.. Nature. 511(7509):319-25.
Tensional homeostasis and the malignant phenotype. Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D et al.. 2005. Tensional homeostasis and the malignant phenotype.. Cancer Cell. 8(3):241-54.
Matrix crosslinking forces tumor progression by enhancing integrin signaling. Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SFT, Csiszar K, Giaccia A, Weninger W et al.. 2009. Matrix crosslinking forces tumor progression by enhancing integrin signaling.. Cell. 139(5):891-906.
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KKC et al.. 2010. HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.. J Clin Invest. 120(5):1535-50.
Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin. Damiano L, Stewart KM, Cohet N, Mouw JK, Lakins JN, Debnath J, Reisman D, Nickerson JA, Imbalzano AN, Weaver VM. 2013. Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin.. Oncogene.
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM et al.. 2014. Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.. Nat Med.