Publications

  1. Przybyla, L., J. N. Lakins, R. Sunyer, X. Trepat, and V. M. Weaver, "Monitoring developmental force distributions in reconstituted embryonic epithelia.", Methods, 2015 Sep 2.
    DOI: 10.1016/j.ymeth.2015.09.003
  2. Acerbi, I., L. Cassereau, I. Dean, Q. Shi, A. Au, C. Park, Y. Y. Chen, J. Liphardt, E. S. Hwang, and V. M. Weaver, "Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration.", Integr Biol (Camb), 2015 May 11.
    DOI: 10.1039/c5ib00040h
  3. Cassereau, L., Y. A. Miroshnikova, G. Ou, J. Lakins, and V. M. Weaver, "A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype.", J Biotechnol, vol. 193, pp. 66-9, 2015 Jan 10.
    DOI: 10.1016/j.jbiotec.2014.11.008
  4. Tung, J. C., M. J Barnes, S. R. Desai, C. Sistrunk, M. W. Conklin, P. Schedin, K. W. Eliceiri, P. J. Keely, V. L. Seewaldt, and V. M. Weaver, "Tumor mechanics and metabolic dysfunction.", Free Radic Biol Med, vol. 79, pp. 269-80, 2015 Feb.
    DOI: 10.1016/j.freeradbiomed.2014.11.020
  5. Ou, G., and V. Marie Weaver, "Tumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells.", Bioessays, vol. 37, issue 12, pp. 1293-7, 2015 Dec.
    DOI: 10.1002/bies.201500090
  6. Northcott, J. M., J. J. Northey, M. J Barnes, and V. M. Weaver, "Fighting the force: Potential of homeobox genes for tumor microenvironment regulation.", Biochim Biophys Acta, vol. 1855, issue 2, pp. 248-253, 2015 Apr.
    DOI: 10.1016/j.bbcan.2015.03.004
  7. Rubashkin, M. G., L. Cassereau, R. Bainer, C. C. DuFort, Y. Yui, G. Ou, M. J. Paszek, M. W. Davidson, Y-Y. Chen, and V. M. Weaver, "Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.", Cancer Res, vol. 74, issue 17, pp. 4597-611, 2014 Sep 1.
    DOI: 10.1158/0008-5472.CAN-13-3698
  8. Pickup, M. W., J. K. Mouw, and V. M. Weaver, "The extracellular matrix modulates the hallmarks of cancer.", EMBO Rep, 2014 Nov 8.
    DOI: 10.15252/embr.201439246
  9. Mouw, J. K., G. Ou, and V. M. Weaver, "Extracellular matrix assembly: a multiscale deconstruction.", Nat Rev Mol Cell Biol, 2014 Nov 5.
    DOI: 10.1038/nrm3902
  10. Weaver, V. Marie, "The microenvironment matters.", Mol Biol Cell, vol. 25, issue 21, pp. 3254-8, 2014 Nov 1.
    DOI: 10.1091/mbc.E14-06-1080
  11. Rubashkin, M. G., G. Ou, and V. M. Weaver, "Deconstructing Signaling in 3 Dimensions.", Biochemistry, 2014 Mar 20.
    DOI: 10.1021/bi401710d
  12. Mouw, J. K., Y. Yui, L. Damiano, R. O. Bainer, J. N. Lakins, I. Acerbi, G. Ou, A. C. Wijekoon, K. R. Levental, P. M. Gilbert, et al., "Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.", Nat Med, 2014 Mar 16.
    DOI: 10.1038/nm.3497
  13. Paszek, M. J., C. C. DuFort, O. Rossier, R. Bainer, J. K. Mouw, K. Godula, J. E. Hudak, J. N. Lakins, A. C. Wijekoon, L. Cassereau, et al., "The cancer glycocalyx mechanically primes integrin-mediated growth and survival.", Nature, vol. 511, issue 7509, pp. 319-25, 2014 Jul 17.
    DOI: 10.1038/nature13535
  14. Shi, Q., R. P. Ghosh, H. Engelke, C. H. Rycroft, L. Cassereau, J. A. Sethian, V. M. Weaver, and J. T. Liphardt, "Rapid disorganization of mechanically interacting systems of mammary acini.", Proc Natl Acad Sci U S A, vol. 111, issue 2, pp. 658-63, 2014 Jan 14.
    DOI: 10.1073/pnas.1311312110
  15. Venugopalan, G., D. B. Camarillo, K. D. Webster, C. D. Reber, J. A. Sethian, V. M. Weaver, D. A. Fletcher, H. El-Samad, and C. H. Rycroft, "Multicellular architecture of malignant breast epithelia influences mechanics.", PLoS One, vol. 9, issue 8, pp. e101955, 2014.
    DOI: 10.1371/journal.pone.0101955
  16. Maller, O., K. C. Hansen, T. R. Lyons, I. Acerbi, V. M. Weaver, R. Prekeris, A-C. Tan, and P. Schedin, "Collagen architecture in pregnancy-induced protection from breast cancer.", J Cell Sci, vol. 126, issue Pt 18, pp. 4108-10, 2013 Sep 15.
    DOI: 10.1242/jcs.121590
  17. Pickup, M. W., H. Laklai, I. Acerbi, P. Owens, A. E. Gorska, A. Chytil, M. Aakre, V. M. Weaver, and H. L. Moses, "Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas.", Cancer Res, vol. 73, issue 17, pp. 5336-46, 2013 Sep 1.
    DOI: 10.1158/0008-5472.CAN-13-0012
  18. Tang, Y., G. R Rowe, E. L. Botvinick, A. Kurup, A. J. Putnam, M. Seiki, V. M. Weaver, E. T. Keller, S. Goldstein, J. Dai, et al., "MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.", Dev Cell, vol. 25, issue 4, pp. 402-16, 2013 May 28.
    DOI: 10.1016/j.devcel.2013.04.011
  19. Damiano, L., K. M. Stewart, N. Cohet, J. K. Mouw, J. N. Lakins, J. Debnath, D. Reisman, J. A. Nickerson, A. N. Imbalzano, and V. M. Weaver, "Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin.", Oncogene, 2013 Jun 17.
    DOI: 10.1038/onc.2013.220
  20. Maller, O., C. C. DuFort, and V. M. Weaver, "YAP forces fibroblasts to feel the tension.", Nat Cell Biol, vol. 15, issue 6, pp. 570-2, 2013 Jun.
    DOI: 10.1038/ncb2777
  21. Li, C-R., J. J. - M. Su, W-Y. Wang, M. T. - L. Lee, T-Y. Wang, K-Y. Jiang, C-F. Li, J-M. Hsu, C-K. Chen, M. Chen, et al., "Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer.", Am J Pathol, vol. 182, issue 2, pp. 363-74, 2013 Feb.
    DOI: 10.1016/j.ajpath.2012.10.024
  22. Agus, D. B., J. F. Alexander, W. Arap, S. Ashili, J. E. Aslan, R. H. Austin, V. Backman, K. J. Bethel, R. Bonneau, W-C. Chen, et al., "A physical sciences network characterization of non-tumorigenic and metastatic cells.", Sci Rep, vol. 3, pp. 1449, 2013.
    DOI: 10.1038/srep01449
  23. Cassereau, L., C. C. DuFort, and V. M. Weaver, "Morphogenesis: Laying down the tracks.", Nat Mater, vol. 11, issue 6, pp. 490-2, 2012 Jun.
    DOI: 10.1038/nmat3345
  24. Lu, P., V. M. Weaver, and Z. Werb, "The extracellular matrix: a dynamic niche in cancer progression.", J Cell Biol, vol. 196, issue 4, pp. 395-406, 2012 Feb 20.
    DOI: 10.1083/jcb.201102147
  25. Paszek, M. J., C. C. DuFort, M. G. Rubashkin, M. W. Davidson, K. S. Thorn, J. T. Liphardt, and V. M. Weaver, "Scanning angle interference microscopy reveals cell dynamics at the nanoscale.", Nat Methods, vol. 9, issue 8, pp. 825-7, 2012 Aug.
    DOI: 10.1038/nmeth.2077
  26. Lakins, J. N., A. R. Chin, and V. M. Weaver, "Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels.", Methods Mol Biol, vol. 916, pp. 317-50, 2012.
    DOI: 10.1007/978-1-61779-980-8_24
  27. Lopez, J. I., I. Kang, W-K. You, D. M. McDonald, and V. M. Weaver, "In situ force mapping of mammary gland transformation.", Integr Biol (Camb), vol. 3, issue 9, pp. 910-21, 2011 Sep.
    DOI: 10.1039/c1ib00043h
  28. Dvorak, H. F., V. M. Weaver, T. D. Tlsty, and G. Bergers, "Tumor microenvironment and progression.", J Surg Oncol, vol. 103, issue 6, pp. 468-74, 2011 May 1.
    DOI: 10.1002/jso.21709
  29. DuFort, C. C., M. J. Paszek, and V. M. Weaver, "Balancing forces: architectural control of mechanotransduction.", Nat Rev Mol Cell Biol, vol. 12, issue 5, pp. 308-19, 2011 May.
    DOI: 10.1038/nrm3112
  30. Samuel, M. S., J. I. Lopez, E. J. McGhee, D. R. Croft, D. Strachan, P. Timpson, J. Munro, E. Schröder, J. Zhou, V. G. Brunton, et al., "Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth.", Cancer Cell, vol. 19, issue 6, pp. 776-91, 2011 Jun 14.
    DOI: 10.1016/j.ccr.2011.05.008

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