Publications

  1. Yu, H., J. Kay Mouw, and V. M. Weaver, "Forcing form and function: biomechanical regulation of tumor evolution.", Trends Cell Biol, vol. 21, issue 1, pp. 47-56, 2011 Jan.
    DOI: 10.1016/j.tcb.2010.08.015
  2. Lu, P., K. Takai, V. M. Weaver, and Z. Werb, "Extracellular matrix degradation and remodeling in development and disease.", Cold Spring Harb Perspect Biol, vol. 3, issue 12, 2011 Dec.
    DOI: 10.1101/cshperspect.a005058
  3. Miroshnikova, Y. A., D. M. Jorgens, L. Spirio, M. Auer, A. L. Sarang-Sieminski, and V. M. Weaver, "Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties.", Phys Biol, vol. 8, issue 2, pp. 026013, 2011 Apr.
    DOI: 10.1088/1478-3975/8/2/026013
  4. Brown, X. Q., E. Bartolak-Suki, C. Williams, M. L. Walker, V. M. Weaver, and J. Y. Wong, "Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: implications for atherosclerosis.", J Cell Physiol, vol. 225, issue 1, pp. 115-22, 2010 Oct.
    DOI: 10.1002/jcp.22202
  5. Egeblad, M., M. G. Rasch, and V. M. Weaver, "Dynamic interplay between the collagen scaffold and tumor evolution.", Curr Opin Cell Biol, vol. 22, issue 5, pp. 697-706, 2010 Oct.
    DOI: 10.1016/j.ceb.2010.08.015
  6. Gilbert, P. M., J. K. Mouw, M. A. Unger, J. N. Lakins, M. K. Gbegnon, V. B. Clemmer, M. Benezra, J. D. Licht, N. J. Boudreau, K. K. C. Tsai, et al., "HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.", J Clin Invest, vol. 120, issue 5, pp. 1535-50, 2010 May.
    DOI: 10.1172/JCI39534
  7. Cohet, N., K. M. Stewart, R. Mudhasani, A. J. Asirvatham, C. Mallappa, K. M. Imbalzano, V. M. Weaver, A. N. Imbalzano, and J. A. Nickerson, "SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.", J Cell Physiol, vol. 223, issue 3, pp. 667-78, 2010 Jun.
    DOI: 10.1002/jcp.22072
  8. Frantz, C., K. M. Stewart, and V. M. Weaver, "The extracellular matrix at a glance.", J Cell Sci, vol. 123, issue Pt 24, pp. 4195-200, 2010 Dec 15.
    DOI: 10.1242/jcs.023820
  9. Levental, K. R., H. Yu, L. Kass, J. N. Lakins, M. Egeblad, J. T. Erler, S. F. T. Fong, K. Csiszar, A. Giaccia, W. Weninger, et al., "Matrix crosslinking forces tumor progression by enhancing integrin signaling.", Cell, vol. 139, issue 5, pp. 891-906, 2009 Nov 25.
    DOI: 10.1016/j.cell.2009.10.027
  10. Vasilatos, S. N., G. Broadwater, W. T. Barry, J. C. Baker, S. Lem, E. C. Dietze, G. R. Bean, A. D. Bryson, P. G. Pilie, V. Goldenberg, et al., "CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis.", Cancer Epidemiol Biomarkers Prev, vol. 18, issue 3, pp. 901-14, 2009 Mar.
    DOI: 10.1158/1055-9965.EPI-08-0875
  11. Kumar, S., and V. M. Weaver, "Mechanics, malignancy, and metastasis: the force journey of a tumor cell.", Cancer Metastasis Rev, vol. 28, issue 1-2, pp. 113-27, 2009 Jun.
    DOI: 10.1007/s10555-008-9173-4
  12. Gehler, S., M. Baldassarre, Y. Lad, J. L. Leight, M. A. Wozniak, K. M. Riching, K. W. Eliceiri, V. M. Weaver, D. A. Calderwood, and P. J. Keely, "Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension.", Mol Biol Cell, vol. 20, issue 14, pp. 3224-38, 2009 Jul.
    DOI: 10.1091/mbc.E08-12-1186
  13. Butcher, D. T., T. Alliston, and V. M. Weaver, "A tense situation: forcing tumour progression.", Nat Rev Cancer, vol. 9, issue 2, pp. 108-22, 2009 Feb.
    DOI: 10.1038/nrc2544
  14. Paszek, M. J., D. Boettiger, V. M. Weaver, and D. A. Hammer, "Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate.", PLoS Comput Biol, vol. 5, issue 12, pp. e1000604, 2009 Dec.
    DOI: 10.1371/journal.pcbi.1000604
  15. Engler, A. J., P. O. Humbert, B. Wehrle-Haller, and V. M. Weaver, "Multiscale modeling of form and function.", Science, vol. 324, issue 5924, pp. 208-12, 2009 Apr 10.
    DOI: 10.1126/science.1170107
  16. Erler, J. T., and V. M. Weaver, "Three-dimensional context regulation of metastasis.", Clin Exp Metastasis, vol. 26, issue 1, pp. 35-49, 2009.
    DOI: 10.1007/s10585-008-9209-8
  17. Lopez, J. I., J. K. Mouw, and V. M. Weaver, "Biomechanical regulation of cell orientation and fate.", Oncogene, vol. 27, issue 55, pp. 6981-93, 2008 Nov 24.
    DOI: 10.1038/onc.2008.348
  18. Fournier, A. K., L. E. Campbell, P. Castagnino, W. F. Liu, B. M. Chung, V. M. Weaver, C. S. Chen, and R. K. Assoian, "Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion.", J Cell Sci, vol. 121, issue Pt 2, pp. 226-33, 2008 Jan 15.
    DOI: 10.1242/jcs.017012
  19. Yee, K. L., V. M. Weaver, and D. A. Hammer, "Integrin-mediated signalling through the MAP-kinase pathway.", IET Syst Biol, vol. 2, issue 1, pp. 8-15, 2008 Jan.
    DOI: 10.1049/iet-syb:20060058
  20. Friedland, J. C., J. N. Lakins, M. G. Kazanietz, J. Chernoff, D. Boettiger, and V. M. Weaver, "alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini.", J Cell Sci, vol. 120, issue Pt 20, pp. 3700-12, 2007 Oct 15.
    DOI: 10.1242/jcs.03484
  21. Kass, L., J. T. Erler, M. Dembo, and V. M. Weaver, "Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis.", Int J Biochem Cell Biol, vol. 39, issue 11, pp. 1987-94, 2007.
    DOI: 10.1016/j.biocel.2007.06.025
  22. Paszek, M. J., N. Zahir, K. R. Johnson, J. N. Lakins, G. I. Rozenberg, A. Gefen, C. A. Reinhart-King, S. S. Margulies, M. Dembo, D. Boettiger, et al., "Tensional homeostasis and the malignant phenotype.", Cancer Cell, vol. 8, issue 3, pp. 241-54, 2005 Sep.
    DOI: 10.1016/j.ccr.2005.08.010
  23. Paszek, M. J., and V. M. Weaver, "The tension mounts: mechanics meets morphogenesis and malignancy.", J Mammary Gland Biol Neoplasia, vol. 9, issue 4, pp. 325-42, 2004 Oct.
    DOI: 10.1007/s10911-004-1404-x
  24. Zahir, N., and V. M. Weaver, "Death in the third dimension: apoptosis regulation and tissue architecture.", Curr Opin Genet Dev, vol. 14, issue 1, pp. 71-80, 2004 Feb.
    DOI: 10.1016/j.gde.2003.12.005
  25. Zahir, N., J. N. Lakins, A. Russell, WY. Ming, C. Chatterjee, G. I. Rozenberg, P. M Marinkovich, and V. M. Weaver, "Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors.", J Cell Biol, vol. 163, issue 6, pp. 1397-407, 2003 Dec 22.
    DOI: 10.1083/jcb.200302023
  26. Unger, M., and V. M. Weaver, "The tissue microenvironment as an epigenetic tumor modifier.", Methods Mol Biol, vol. 223, pp. 315-47, 2003.
    DOI: 10.1385/1-59259-329-1:315
  27. Weaver, V. M., S. Lelièvre, J. N. Lakins, M. A. Chrenek, J. C. R. Jones, F. Giancotti, Z. Werb, and M. J. Bissell, "beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium.", Cancer Cell, vol. 2, issue 3, pp. 205-16, 2002 Sep.
    DOI:
  28. Weaver, V. M., "Membrane-associated MMP regulators: novel cell adhesion tumor suppressor proteins?", Dev Cell, vol. 2, issue 1, pp. 6-7, 2002 Jan.
    DOI:
  29. Bissell, M. J., D. C. Radisky, A. Rizki, V. M. Weaver, and O. W. Petersen, "The organizing principle: microenvironmental influences in the normal and malignant breast.", Differentiation, vol. 70, issue 9-10, pp. 537-46, 2002 Dec.
    DOI: 10.1046/j.1432-0436.2002.700907.x
  30. Chrenek, M. A., P. Wong, and V. M. Weaver, "Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation.", Breast Cancer Res, vol. 3, issue 4, pp. 224-9, 2001.
    DOI:

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