Congratulations to Matthew Paszek (now at Cornell University) and all other authors on their recent publication in Nature!
Biblio
MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.. Dev Cell. 25(4):402-16.
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2013. Tumor mechanics and metabolic dysfunction.. Free Radic Biol Med. 79:269-80.
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2015. The tissue microenvironment as an epigenetic tumor modifier.. Methods Mol Biol. 223:315-47.
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2003. CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis.. Cancer Epidemiol Biomarkers Prev. 18(3):901-14.
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2009. Multicellular architecture of malignant breast epithelia influences mechanics.. PLoS One. 9(8):e101955.
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2014. Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology.. Proc Natl Acad Sci U S A. 95(25):14821-6.
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1998. Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes.. J Cell Sci. 109 ( Pt 1):45-56.
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1996. The microenvironment matters.. Mol Biol Cell. 25(21):3254-8.
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2014. The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay.. Biochem Cell Biol. 74(6):833-51.
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1996. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies.. J Cell Biol. 137(1):231-45.
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1997. .
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2002. Integrin-mediated signalling through the MAP-kinase pathway.. IET Syst Biol. 2(1):8-15.
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2008. Forcing form and function: biomechanical regulation of tumor evolution.. Trends Cell Biol. 21(1):47-56.
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2011. Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors.. J Cell Biol. 163(6):1397-407.
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2003. Death in the third dimension: apoptosis regulation and tissue architecture.. Curr Opin Genet Dev. 14(1):71-80.
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2004.