Congratulations to Hanane Laklai and coauthors on their publication in Nature Medicine!
Biblio
In situ force mapping of mammary gland transformation.. Integr Biol (Camb). 3(9):910-21.
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2011. Biomechanical regulation of cell orientation and fate.. Oncogene. 27(55):6981-93.
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2008. Extracellular matrix degradation and remodeling in development and disease.. Cold Spring Harb Perspect Biol. 3(12)
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2011. The extracellular matrix: a dynamic niche in cancer progression.. J Cell Biol. 196(4):395-406.
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2012. Collagen architecture in pregnancy-induced protection from breast cancer.. J Cell Sci. 126(Pt 18):4108-10.
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2013. YAP forces fibroblasts to feel the tension.. Nat Cell Biol. 15(6):570-2.
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2013. Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties.. Phys Biol. 8(2):026013.
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2011. Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.. Nat Med.
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2014. Extracellular matrix assembly: a multiscale deconstruction.. Nat Rev Mol Cell Biol.
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2014. Fighting the force: Potential of homeobox genes for tumor microenvironment regulation.. Biochim Biophys Acta. 1855(2):248-253.
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2015. .
2015.
The cancer glycocalyx mechanically primes integrin-mediated growth and survival.. Nature. 511(7509):319-25.
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2014. The tension mounts: mechanics meets morphogenesis and malignancy.. J Mammary Gland Biol Neoplasia. 9(4):325-42.
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2004. Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate.. PLoS Comput Biol. 5(12):e1000604.
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2009. Tensional homeostasis and the malignant phenotype.. Cancer Cell. 8(3):241-54.
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2005. Scanning angle interference microscopy reveals cell dynamics at the nanoscale.. Nat Methods. 9(8):825-7.
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2012. A physical sciences network characterization of non-tumorigenic and metastatic cells.. Sci Rep. 3:1449.
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2015. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.. Cancer Res. 74(17):4597-611.
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2014. Deconstructing Signaling in 3 Dimensions.. Biochemistry.
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2014. Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth.. Cancer Cell. 19(6):776-91.
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2011. Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype.. J Mammary Gland Biol Neoplasia. 3(2):201-13.
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1998. Rapid disorganization of mechanically interacting systems of mammary acini.. Proc Natl Acad Sci U S A. 111(2):658-63.
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2014.